The Merck Group Website
The Merck Group Website

Adult Growth Hormone Deficiency

Adult Growth Hormone
A condition that also affects adults
Growth hormone (GH) regulates a number of metabolic and physiological processes throughout life. GH deficiency occurs when the pituitary gland in the brain is unable to produce or release sufficient amounts of growth hormone.
Growth deficiencies do not just affect children – they can be a significant problem for adults, too. Adult GHD is now recognized as a specific clinical syndrome with numerous physiological consequences, including effects on:
 
  • Body composition, including central obesity
  • Lipids in the blood
  • Muscle strength
  • Bone composition
  • Exercise capacity and energy
  • Cardiovascular risk
  • Psychological well-being
GHD in adults can result from a pituitary or peri-pituitary tumor or as a direct result of surgery or radiation used to manage these conditions. Less commonly, GHD in adults arises from a deficiency acquired in childhood.
In adults, the signs of GHD may include psychological symptoms such as depression, anxiety, poor memory and social isolation as well as physiological problems such as weakness, poor vitality, easy fatigue and weight gain.   
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